Eukaryotic promoter prediction tools

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Wei, L. Promoters are crucial regulatory DNA regions for gene transcriptional activation. Rapid advances in next-generation sequencing technologies have accelerated the accumulation of genome sequences, providing increased training data to inform computational approaches for both prokaryotic and eukaryotic promoter prediction. However, it remains a significant challenge to accurately identify species-specific promoter sequences using computational approaches.

EP3 is fast, it can make predictions for a whole genome animals, plants, etc. EP3 is accurate: it performs better than the current state-of-the-art promoter prediction programs on the human genome. EP3 requires no training is is applicable to all eukaryotic genomes.